E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson’s Disease model
Ze Zhao, Xiaomeng Song, Yimeng Wang, Lu Yu, Gan Huang, Yiquan Li, Runzhe Zong, Tengfei Liu, Qiuran Ji, Yi Zheng, Bingyu Liu, Qingfen Zhu, Lin Chen, Chengjiang Gao, Huiqing Liu
Topics & Concepts
VDAC1Ubiquitin ligaseNeurodegenerationUbiquitinMPTPProteasomeNeuroprotectionCell biologyParkinson's diseaseDopaminergicProtein degradationBiologyChemistryPharmacologyBiochemistryMedicineNeuroscienceDopamineDiseaseInternal medicineBacterial outer membraneEscherichia coliGeneAutophagy in Disease and TherapyParkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathways