AAV3-miRNA vectors for growth suppression of human hepatocellular carcinoma cells in vitro and human liver tumors in a murine xenograft model in vivo
Ling Yin, Geoffrey D. Keeler, Yuanhui Zhang, Brad E. Hoffman, Chen Ling, Keyun Qing, Arun Srivastava
Topics & Concepts
In vivoBiologyCancer researchHepatocellular carcinomaGenetic enhancementCell cultureViral vectorMiR-122microRNACell growthIn vitroLuciferaseVector (molecular biology)Molecular biologyVirologyTransfectionRecombinant DNAVirusGeneHepatitis C virusBiochemistryGeneticsBiotechnologyVirus-based gene therapy researchRNA Interference and Gene DeliveryBacteriophages and microbial interactions