Generation of Lungs by Blastocyst Complementation in Apneumic Fgf10-Deficient Mice
Akihiko Kitahara, Qingsong Ran, Kanako Oda, Akihiro Yasue, Manabu Abe, Xulu Ye, Toshikuni Sasaoka, Masanori Tsuchida, Kenji Sakimura, Yoichi Ajioka, Yasuo Saijo, Qiliang Zhou
Abstract
blastocysts provide an organ niche for lung generation and that blastocyst complementation could be a viable approach for generating whole lungs.
Topics & Concepts
BlastocystEmbryonic stem cellComplementationInduced pluripotent stem cellBiologyLungCell biologyEmbryoImmunologyPathologyMedicineInternal medicineEmbryogenesisPhenotypeGeneticsGeneRenal and related cancersTissue Engineering and Regenerative MedicinePluripotent Stem Cells Research