A green and sustainable UV spectrophotometric approach for simultaneous determination of rosuvastatin, pravastatin, and atorvastatin in pharmaceuticals leveraging firefly algorithm-enhanced partial least squares regression
Farooq M. Almutairi, Yusuf S. Althobaiti, Maram H. Abduljabbar, Rami M. Alzhrani, Reem M. Alnemari, Muneef M. Aldhafeeri, Ahmed Serag, Atiah H. Almalki
Abstract
75.8% for HPLC-UV). In conclusion, the proposed UV-PLS-FFA method offers an effective, accurate, and environmentally friendly alternative for the determination of statins in pharmaceutical samples, aligning with the principles of green chemistry and sustainability and has potential for broader applicability beyond the scope of this study.
Topics & Concepts
RosuvastatinPravastatinAtorvastatinPartial least squares regressionFirefly algorithmChemistryMathematicsAlgorithmPharmacologyStatisticsMedicineBiochemistryCholesterolParticle swarm optimizationAnalytical Methods in PharmaceuticalsComputational Drug Discovery Methods