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Molecular mechanisms of metabotropic GABA <sub>B</sub> receptor function

Hamidreza Shaye, Benjamin Stauch, Cornelius Gati, Vadim Cherezov

2021Science Advances108 citationsDOIOpen Access PDF

Abstract

receptor, which not only broaden our understanding of its structure, pharmacology, and physiological effects but also will ultimately facilitate the discovery of new therapeutic drugs and neuromodulators.

Topics & Concepts

Metabotropic receptorMetabotropic glutamate receptorNeuroscienceMechanism (biology)Metabotropic glutamate receptor 1ReceptorMetabotropic glutamate receptor 7Metabotropic glutamate receptor 5Metabotropic glutamate receptor 4ChemistryBiologyBiochemistryGlutamate receptorPhysicsQuantum mechanicsNeuroscience and Neuropharmacology ResearchReceptor Mechanisms and SignalingTryptophan and brain disorders
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