Polymer grafted magnetic graphene oxide as a potential nanocarrier for pH-responsive delivery of sparingly soluble quercetin against breast cancer cells
Monika Matiyani, Anita Rana, Mintu Pal, Sravendra Rana, Anand B. Melkani, Nanda Gopal Sahoo
Abstract
nanohybrid was found to be more toxic than the free drug towards MDA MB 231 cells and exhibits biocompatibility towards HEK 293T cells. Overall, a smart drug delivery system including polymer grafted magnetic graphene oxide as a pH-responsive potential nanocarrier could be beneficial for targeted drug delivery, controlled by an external magnetic field as an advancement in chemotherapy against cancer.
Topics & Concepts
NanocarriersQuercetinChemistryGrapheneOxidePolymerBreast cancerNanotechnologyCancerChemical engineeringMaterials scienceDrug deliveryOrganic chemistryMedicineInternal medicineEngineeringAntioxidantGraphene and Nanomaterials ApplicationsNanoparticle-Based Drug DeliveryGraphene research and applications