NQO1 regulates cell cycle progression at the G2/M phase
Eun‐Taex Oh, Ha Gyeong Kim, Chul Hoon Kim, Jeonghun Lee, Chulhee Kim, Jae‐Seon Lee, Yunmi Cho, Heon Joo Park
Abstract
Collectively, our results support a novel regulatory role of NQO1 in the mechanism of cell cycle progression at the G2/M phase in cancer through effects on c‑Fos/CKS1 signaling.
Topics & Concepts
Cell cycle progressionCell cycleCell biologyChemistryCellCancer researchBiologyBiochemistryGenomics, phytochemicals, and oxidative stressCoenzyme Q10 studies and effectsBioactive Compounds and Antitumor Agents