Litcius/Paper detail

Chloroquine: Can it be a Novel Drug for COVID-19.

Dinesh Badyal, Rajiv Mahajan

2020PubMed14 citationsDOIOpen Access PDF

Abstract

Coronavirus disease 2019 (COVID-19) has been declared a pandemic by the World Health Organization. The United States Food and Drug Administration has not approved any drug or vaccine for the treatment of COVID-19; however, reports have emerged from different parts of the world about the potential therapeutic benefits of existing drugs. Chloroquine and phosphate hydroxychloroquine are the drugs currently in the limelight, and recently, the National Task Force for COVID-19 constituted by the Indian Council of Medical Research has recommended the use of antimalarial drug hydroxychloroquine for prophylaxis of severe acute respiratory syndrome-coronavirus 2 infection in selected high-risk individuals. This short write-up explores the potential efficacy and established safety of chloroquine in COVID-19.

Topics & Concepts

ChloroquineHydroxychloroquinePandemicDrugCoronavirus disease 2019 (COVID-19)MedicineCoronavirusFood and drug administrationNew drug applicationDrug repositioningIntensive care medicineLimelightPharmacologyVirologyDiseaseMalariaInfectious disease (medical specialty)ImmunologyInternal medicineElectrical engineeringEngineeringCOVID-19 Clinical Research StudiesDrug-Induced Hepatotoxicity and ProtectionVitamin C and Antioxidants Research