Identification of KPC-112 from an ST15 Klebsiella pneumoniae Strain Conferring Resistance to Ceftazidime-Avibactam
Siquan Shen, Chengkang Tang, Li Ding, Renru Han, Dandan Yin, Weiwei Yang, Yan Guo, Fupin Hu
Abstract
isolates producing these kinds of KPC variants might be missed by conventional antimicrobial susceptibility testing (AST) methods and lead to irrational drug use. So, this study of KPC-112 will help to establish the diversity of KPCs and remind researchers of the challenge of drug resistance and detection brought by the KPC variants.
Topics & Concepts
Ceftazidime/avibactamKlebsiella pneumoniaeStrain (injury)Identification (biology)CeftazidimeMicrobiologyAntibiotic resistanceKlebsiellaBiologyBacteriaEscherichia coliAntibioticsPseudomonas aeruginosaGeneticsGeneEcologyAnatomyAntibiotic Resistance in BacteriaEnterobacteriaceae and Cronobacter ResearchPharmaceutical and Antibiotic Environmental Impacts