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Addressing the Enzyme-independent tumor-promoting function of NAMPT via PROTAC-mediated degradation

Xiaotong Zhu, Haixia Liu, Li Chen, Chenxu Wu, Xuesong Liu, Yong Cang, Biao Jiang, Xiaobao Yang, Gaofeng Fan

2022Cell chemical biology29 citationsDOI

Topics & Concepts

Nicotinamide phosphoribosyltransferaseNAD+ kinaseNicotinamide adenine dinucleotideProteolysisEnzymeCell biologyCancer researchBiochemistryProtein degradationChemistryBiologyProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis
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