The preferential effect of Clemastine on F3/Contactin-1/Notch-1 compared to Jagged-1/Notch-1 justifies its remyelinating effect in an experimental model of multiple sclerosis in rats
Sherehan M. Ibrahim, Ahmed S. Kamel, Kawkab A. Ahmed, Reham A. Mohammed, Reham M. Essam
Topics & Concepts
Experimental autoimmune encephalomyelitisMyelin basic proteinOligodendrocyteNotch signaling pathwayInternal medicineMyelinMedicineNeuroscienceChemistryImmunologyEndocrinologyMultiple sclerosisReceptorBiologyCentral nervous systemNeuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanismsCell Adhesion Molecules Research