COVID-19 Drugs Chloroquine and Hydroxychloroquine, but Not Azithromycin and Remdesivir, Block hERG Potassium Channels
Mark Szendrey, Jun Guo, Wentao Li, Tonghua Yang, Shetuan Zhang
Topics & Concepts
hERGHydroxychloroquineChloroquinePharmacologyQT intervalMedicinePotassium channelAzithromycinLong QT syndromeTorsades de pointesPotassium channel blockerDrugCoronavirus disease 2019 (COVID-19)AnesthesiaInternal medicineChemistryImmunologyBiochemistryMalariaDiseaseAntibioticsInfectious disease (medical specialty)Cardiac electrophysiology and arrhythmiasIon channel regulation and functionReceptor Mechanisms and Signaling