Selective Synthesis of Phenanthrenes and Dihydrophenanthrenes via Gold-Catalyzed Cycloisomerization of Biphenyl Embedded Trienynes
Ana Milián, Patricia García‐García, Adrián Pérez‐Redondo, Roberto Sanz, Juan J. Vaquero, Manuel A. Fernández‐Rodríguez
Abstract
-alkynylbiaryls, a particular type of 1,7-enynes, undergo a selective cycloisomerization reaction in the presence of a gold(I) catalyst to give interesting phenanthrene and dihydrophenanthrene derivatives in high yields. The solvent used provokes a switch in the evolution of the gold intermediate and plays a key role in the reaction outcome.
Topics & Concepts
CycloisomerizationPhenanthrenesChemistryCatalysisPhenanthreneBiphenylSolventCombinatorial chemistryOrganic chemistryCatalytic Alkyne ReactionsCyclopropane Reaction MechanismsSulfur-Based Synthesis Techniques