Toward understanding links between the microbiome and neurotransmitters
Jonathan B. Lynch, Elaine Y. Hsiao
Abstract
The gut microbiota modulates neurobiological activity in various animal lineages. This is often proposed to occur through interactions with neurotransmitters and other neuromodulatory molecules in the host. Our commentary will discuss recent research that establishes microbiota-neurotransmitter connections, gaps in current understanding, and outstanding questions that may guide future advances in the field of microbiota-nervous system interactions.
Topics & Concepts
MicrobiomeComputational biologyChemistryBiochemical engineeringNeuroscienceData scienceComputer scienceBiologyBioinformaticsEngineeringTryptophan and brain disordersGut microbiota and healthNeuroendocrine regulation and behavior