Inhibition of TNFR1 Attenuates LPS Induced Apoptosis and Inflammation in Human Nucleus Pulposus Cells by Regulating the NF-KB and MAPK Signalling Pathway
Feng Lv, Longbiao Yang, Jianxiu Wang, Zhixiang Chen, Qizhao Sun, Peiguo Zhang, Chentong Guan, Yanbin Liu
Topics & Concepts
Tumor necrosis factor receptor 1MAPK/ERK pathwayApoptosisInflammationCell biologyTumor necrosis factor alphaSignal transductionReceptorNucleusBlockadeProgrammed cell deathPharmacologyChemistryBiologyCancer researchImmunologyBiochemistryTumor necrosis factor receptorSpine and Intervertebral Disc PathologyMusculoskeletal pain and rehabilitationMedical Imaging and Analysis