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Oxidative stress and TGF-β1 induction by metformin in MCF-7 and MDA-MB-231 human breast cancer cells are accompanied with the downregulation of genes related to cell proliferation, invasion and metastasis

Poliana Camila Marinello, Carolina Panis, Thamara Nishida Xavier da Silva, Renata Binato, Eliana Abdelhay, Juliana Alves Rodrigues, André Luiz Mencalha, Natália Medeiros Dias Lopes, Fernando H. Borges, Rodrigo Cabral Luiz, Rúbens Cecchini, Alessandra Lourenço Cecchini

2020Pathology - Research and Practice15 citationsDOI

Topics & Concepts

MetforminCancer researchMCF-7MetastasisTransforming growth factorCytotoxic T cellDownregulation and upregulationCancer cellCell growthBiologyEpithelial–mesenchymal transitionCancerCancer stem cellMedicineInternal medicineEndocrinologyGeneDiabetes mellitusBiochemistryIn vitroHuman breastMetabolism, Diabetes, and CancerCancer, Hypoxia, and MetabolismCancer-related Molecular Pathways
Oxidative stress and TGF-β1 induction by metformin in MCF-7 and MDA-MB-231 human breast cancer cells are accompanied with the downregulation of genes related to cell proliferation, invasion and metastasis | Litcius