Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity
Bola S. Hanna, Laura Llaó Cid, Murat Iskar, Philipp M. Roessner, Lara C. Klett, John Wong, Yashna Paul, Nikolaos Ioannou, Selcen Öztürk, Norman Mack, Verena Kalter, Dolors Colomer, Elı́as Campo, Johannes Bloehdorn, Stephan Stilgenbauer, Sascha Dietrich, Manfred Schmidt, Richard Gabriel, Karsten Rippe, Markus Feuerer, Alan G. Ramsay, Peter Lichter, Marc Zapatka, Martina Seiffert
Topics & Concepts
BiologyCD8NFATCytotoxic T cellT cellImmunologyPopulationCancer researchZAP70ImmunityInterleukin 21Immune systemTranscription factorMedicineEnvironmental healthGeneIn vitroBiochemistryImmune Cell Function and InteractionCancer Immunotherapy and BiomarkersCAR-T cell therapy research