IQGAP3 interacts with Rad17 to recruit the Mre11-Rad50-Nbs1 complex and contributes to radioresistance in lung cancer
Yulan Zeng, Xiaohua Jie, Bian Wu, Gang Wu, Li Liu, Shuangbing Xu
Topics & Concepts
RadioresistanceBiologyCarcinogenesisCancer researchLung cancerRad50DNA damageDNA repairCancerDownregulation and upregulationCell biologyPathologyTranscription factorMedicineGeneticsCell cultureDNADNA-binding proteinGeneDNA Repair MechanismsCancer-related Molecular PathwaysGenomics and Chromatin Dynamics