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Potential mechanism of action of<i>Ixeris sonchifolia</i>extract injection against cardiovascular diseases revealed by combination of HPLC-Q-TOF-MS, virtual screening and systems pharmacology approach

Rongfang Xie, Zhenzhen Liu, Zuan Lin, Peiying Shi, Bing Chen, Shaoguang Li, Guangwen Li, Liying Huang, Xinhua Lin, Hong Yao

2020RSC Advances13 citationsDOIOpen Access PDF

Abstract

<italic>Ixeris sonchifolia</italic>extract injection, a Chinese medicine preparation named as Kudiezi injection (KDZI) in China, has been widely used for the treatment of cardiovascular diseases (CVDs) in recent years.

Topics & Concepts

LuteolinCaffeic acidChemistryPharmacologyVirtual screeningApigeninTraditional medicineKEGGBiochemistryMedicineAntioxidantDrug discoveryFlavonoidTranscriptomeGeneGene expressionNatural product bioactivities and synthesisPhytochemistry and Biological ActivitiesSesquiterpenes and Asteraceae Studies
Potential mechanism of action of<i>Ixeris sonchifolia</i>extract injection against cardiovascular diseases revealed by combination of HPLC-Q-TOF-MS, virtual screening and systems pharmacology approach | Litcius