Obeticholic Acid Ameliorates Valproic Acid–Induced Hepatic Steatosis and Oxidative Stress
Zhibo Gai, E.I. Krajnc, Sophia L. Samodelov, Michele Visentin, Gerd A. Kullak‐Ublick
Topics & Concepts
Farnesoid X receptorSteatosisValproic AcidOxidative stressPeroxisome proliferator-activated receptorLipid metabolismTauroursodeoxycholic acidChemistryNuclear receptorCytochrome P450CYP8B1PharmacologyEndocrinologyLipid peroxidationCYP2E1Liver injuryChenodeoxycholic acidInternal medicineBile acidBiologyUnfolded protein responseBiochemistryEndoplasmic reticulumReceptorCholesterol 7 alpha-hydroxylaseMetabolismTranscription factorMedicineEpilepsyNeuroscienceGeneDrug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesHIV/AIDS drug development and treatment