Catalytic Decarboxylative Fluorosulfonylation Enabled by Energy-Transfer-Mediated Photocatalysis
Zhida Chen, Xiang Zhou, Ji-Tao Yi, Hongjuan Diao, Qilong Chen, Gui Lu, Jiang Weng
Abstract
Sulfonyl fluorides are useful building blocks in a wide array of fields. Herein, we report a catalytic decarboxylative fluorosulfonylation approach for converting abundant aliphatic carboxylic acids to the corresponding sulfonyl fluorides. This transformation is enabled by simple preactivation as aldoxime esters and energy-transfer-mediated photocatalysis. This operationally simple method proceeds with high functional-group tolerance under mild and redox-neutral conditions.
Topics & Concepts
ChemistrySulfonylPhotocatalysisCatalysisFunctional groupDecarboxylationRedoxCombinatorial chemistryOrganic chemistryPhotochemistryPolymerAlkylSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsFluorine in Organic Chemistry