Redox stress and metal dys-homeostasis appear as hallmarks of early prion disease pathogenesis in mice
Jereme G. Spiers, Hsiao‐Jou Cortina Chen, Tiffany L. Barry, Julie-Myrtille Bourgognon, Joern R. Steinert
Topics & Concepts
Oxidative stressUnfolded protein responseNeurodegenerationHomeostasisSOD1ProteostasisAutophagyEndoplasmic reticulumCell biologySuperoxide dismutaseProtein aggregationBiologyPathogenesisChemistryDiseaseBiochemistryImmunologyMedicineInternal medicineApoptosisPrion Diseases and Protein MisfoldingTrace Elements in HealthAlzheimer's disease research and treatments