Persulfidation is the mechanism underlying sulfide-signaling of autophagy
Cecilia Gotor, Ángeles Aroca, Luís C. Romero
Abstract
S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a conserved molecular mechanism.
Topics & Concepts
AutophagyMechanism (biology)BiologyCysteinePosttranslational modificationCell biologySignal transductionBiochemistryEnzymeApoptosisPhilosophyEpistemologySulfur Compounds in BiologyAutophagy in Disease and TherapyPolyamine Metabolism and Applications