Heterocycloalkynes Fused to a Heterocyclic Core: Searching for an Island with Optimal Stability-Reactivity Balance
Natalia A. Danilkina, Anastasia I. Govdi, Alexander F. Khlebnikov, Alexander O. Tikhomirov, Vladimir V. Sharoyko, Andrey A. Shtyrov, Mikhail N. Ryazantsev, Stefan Bräse, Ирина А. Балова
Abstract
for in vitro bioconjugation was exemplified by labeling and visualization of HEK293 cells carrying azido-DNA and azido-glycans.
Topics & Concepts
ChemistryBenzothiopheneReactivity (psychology)HeteroatomBioconjugationCombinatorial chemistryComputational chemistryAlkyneSonogashira couplingCycloadditionRing strainBioorthogonal chemistryStereochemistryMoleculeRing (chemistry)ThiopheneOrganic chemistryClick chemistryPalladiumPathologyAlternative medicineMedicineCatalysisClick Chemistry and ApplicationsChemical Synthesis and AnalysisBiochemical and Structural Characterization