Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis
Wanyan Deng, Yang Bai, Fan Deng, Youdong Pan, Shenglin Mei, Zengzhang Zheng, Rui Min, Zeyu Wu, Wu Li, Rui Miao, Zhibin Zhang, Thomas S. Kupper, Judy Lieberman, Xing Liu
Topics & Concepts
PyroptosisStreptococcus pyogenesVirulenceImmune systemProteasesVirulence factorMicrobiologyEffectorPathogenCaspase 1ExotoxinBiologyCysteine proteaseInflammasomeImmunologyBacteriaInflammationStaphylococcus aureusBiochemistryGeneticsEnzymeToxinGeneInflammasome and immune disordersStreptococcal Infections and TreatmentsBartonella species infections research