Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
Kira Young, Elizabeth Eudy, Rebecca K. Bell, Matthew A. Loberg, Timothy M. Stearns, Devyani Sharma, Lars Velten, Simon Haas, Marie–Dominique Filippi, Jennifer J. Trowbridge
Topics & Concepts
BiologyHaematopoiesisBone marrowStem cellHematopoietic stem cellCell biologyCancer researchImmunologyHematopoietic Stem Cell TransplantationAcute Myeloid Leukemia ResearchGrowth Hormone and Insulin-like Growth Factors