Risk Stratification Using High-Sensitivity Cardiac Troponin T in Patients With Suspected Acute Coronary Syndrome
Andrew R. Chapman, Dennis Sandeman, Amy V. Ferry, Stacey Stewart, Fiona E. Strachan, Ryan Wereski, Anda Bularga, Atul Anand, Anoop Shah, Nicholas L. Mills
Abstract
High-sensitivity cardiac troponin assays allow the early recognition of myocardial injury, and they have facilitated the development of early rule-out pathways to identify patients who do not have acute myocardial infarction. Although international guidelines recommend using the sex-specific 99th centile from a healthy reference population as the diagnostic threshold for myocardial infarction, it is increasingly evident that the use of lower thresholds to risk-stratify patients and rule-out myocardial infarction at presentation is safer and more effective.
Topics & Concepts
MedicineAcute coronary syndromeCardiologyMyocardial infarctionInternal medicineRisk stratificationTroponinAcute Myocardial Infarction ResearchCoronary Interventions and DiagnosticsAtrial Fibrillation Management and Outcomes