Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits
Roshni Patel, Shaila Musharoff, Jeffrey P. Spence, Harold Pimentel, Catherine Tcheandjieu, Hakhamanesh Mostafavi, Nasa Sinnott-Armstrong, Shoa L. Clarke, Courtney J. Smith, Peter Durda, Kent D. Taylor, Russell P. Tracy, Ching‐Ti Liu, W. Craig Johnson, François Aguet, Kristin Ardlie, Stacey Gabriel, J. G. Smith, Deborah A. Nickerson, Stephen S. Rich, Jerome I. Rotter, Philip S. Tsao, Themistocles L. Assimes, Jonathan K. Pritchard
Topics & Concepts
BiologyGeneticsSingle-nucleotide polymorphismGenome-wide association studyGenetic associationEpistasisGeneTraitGenetic genealogyGenetic architectureExpression quantitative trait lociQuantitative trait locusEvolutionary biologyGenotypePopulationDemographyComputer scienceSociologyProgramming languageGenetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock