Novel hybrids of quinoline with pyrazolylchalcones as potential antimalarial agents: Synthesis, biological evaluation, molecular docking and ADME prediction
Ajay Kumar, Sandeep Jain, Shilpi Chauhan, Shilpy Aggarwal, Deepika Saini
Topics & Concepts
ADMEChemistryDocking (animal)In silicoQuinolineStereochemistryAntimalarial AgentPyrazoleCombinatorial chemistryCarbon-13 NMRPlasmodium bergheiIn vitroPlasmodium falciparumBiochemistryOrganic chemistryBiologyGeneMalariaNursingMedicineImmunologySynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsComputational Drug Discovery Methods