Litcius/Paper detail

Multiple Protein Profiler 1.0 (MPP): A Webserver for Predicting and Visualizing Physiochemical Properties of Proteins at the Proteome Level

Gustavo Sganzerla Martinez, Mansi Dutt, Anuj Kumar, David J. Kelvin

2024The Protein Journal30 citationsDOIOpen Access PDF

Abstract

Determining the physicochemical properties of a protein can reveal important insights in their structure, biological functions, stability, and interactions with other molecules. Although tools for computing properties of proteins already existed, we could not find a comprehensive tool that enables the calculations of multiple properties for multiple input proteins on the proteome level at once. Facing this limitation, we developed Multiple Protein Profiler (MPP) 1.0 as an integrated tool that allows the profiling of 12 individual properties of multiple proteins in a significant manner. MPP provides a tabular and graphic visualization of properties of multiple proteins. The tool is freely accessible at https://mproteinprofiler.microbiologyandimmunology.dal.ca/ .

Topics & Concepts

ProteomeVisualizationComputer scienceComputational biologyProfiling (computer programming)BioinformaticsBiologyData miningOperating systemAdvanced Proteomics Techniques and ApplicationsGlycosylation and Glycoproteins ResearchEnzyme Structure and Function