Development of 2-chloroquinoline based heterocyclic frameworks as dual inhibitors of SARS-CoV-2 MPro and PLPro
Bhavita Kattula, Bharati Reddi, Aruna Jangam, L.R. Naik, Bala Manikanta Adimoolam, V. Suresh, Sayanna Are, Jagadeshwar Reddy Thota, Surender Singh Jadav, Mohammed Arifuddin, A. Addlagatta
Topics & Concepts
ChemistryProteasesCytotoxicityMoietyStereochemistryImineProteaseEnzymeSmall moleculeCombinatorial chemistryBiochemistryIn vitroCatalysisSynthesis and biological activityComputational Drug Discovery MethodsClick Chemistry and Applications