Visualized podocyte-targeting and focused ultrasound responsive glucocorticoid nano-delivery system against immune-associated nephropathy without glucocorticoid side effect
Kui Fan, Zeng Li, Jing Guo, Shuqin Xie, Yuan Yu, Jianwei Chen, Jin Cao, Qinyanqiu Xiang, Siliang Zhang, Yuanli Luo, Qingyue Deng, Qin Zhou, Yan Zhao, Lan Hao, Zhigang Wang, Ling Zhong
Abstract
This study provides a promising strategy of Dex/PFP@LIPs-BMS-α as effective and safe against immune-associated nephropathy.
Topics & Concepts
GlucocorticoidPodocyteImmune systemMedicineImmunologyInternal medicineKidneyProteinuriaRenal Diseases and GlomerulopathiesSystemic Lupus Erythematosus ResearchUltrasound and Hyperthermia Applications