ATXN2-mediated translation of TNFR1 promotes esophageal squamous cell carcinoma via m6A-dependent manner
Rui Li, Lingxing Zeng, Hongzhe Zhao, Junge Deng, Ling Pan, Shaoping Zhang, Guandi Wu, Ying Ye, Jialiang Zhang, Jiachun Su, Yanfen Zheng, Shuang Deng, Ruihong Bai, Lisha Zhuang, Mei Li, Zhixiang Zuo, Dongxin Lin, Jian Zheng, Xudong Huang
Abstract
A-TNFRSF1A axis is critical for ESCC development and thus may serve as a potential druggable target.
Topics & Concepts
Translation (biology)Esophageal squamous cell carcinomaBasal cellCancer researchMedicineCarcinomaBiologyChemistryInternal medicineCell biologyBiochemistryMessenger RNAGeneRNA modifications and cancerCancer-related gene regulationRNA Research and Splicing