Temporal and spatial effect of air pollution on hospital admissions for myocardial infarction: a case-crossover study
Xiaoxiao Liu, Stefania Bertazzon, Paul J. Villeneuve, Markey Johnson, Dave Stieb, Stephanie Coward, Divine Tanyingoh, Joseph W. Windsor, Fox E. Underwood, Michael D. Hill, Doreen M. Rabi, William A. Ghali, Stephen B. Wilton, Matthew T. James, Michelle M. Graham, M. Sean McMurtry, Gilaad G. Kaplan
Abstract
BACKGROUND: In studies showing associations between ambient air pollution and myocardial infarction (MI), data have been lacking on the inherent spatial variability of air pollution. The aim of this study was to determine whether the long-term spatial distribution of air pollution influences short-term temporal associations between air pollution and admission to hospital for MI. METHODS: concentrations derived from land use regression models; results of these analyses are presented as odds ratios (ORs) with 95% confidence intervals (CIs). RESULTS: tertiles, the AQHI score was associated with MI (e.g., 5-day average OR 1.13, 95% CI 1.02-1.24, per IQR; 3-day average OR 1.13, 95% CI 1.04-1.23, per IQR). INTERPRETATION: concentrations. Individuals living in neighbourhoods with higher traffic-related pollution should be advised of the health risks and be attentive to special air quality warnings.