Identification of indole-grafted pyrazolopyrimidine and pyrazolopyridine derivatives as new anti-cancer agents: Synthesis, biological assessments, and molecular modeling insights
Wagdy M. Eldehna, Haytham O. Tawfik, Maha‐Hamadien Abdulla, Mohamed S. Nafie, Heba Aref, Moataz A. Shaldam, Noura Alhassan, Omar Al Obeed, Zainab M. Elsayed, Hatem A. Abdel‐Aziz
Topics & Concepts
ChemistryCytotoxicityPancreatic cancerCancer researchKinaseLung cancerCancerIndole testCancer cellDrug discoveryCell growthPharmacologyBiochemistryIn vitroBiologyOncologyMedicineInternal medicineCancer Mechanisms and TherapySynthesis and biological activityQuinazolinone synthesis and applications