ZIF-8 integrated with polydopamine coating as a novel nano-platform for skin-specific drug delivery
Qiuyue Wang, Mingming Li, Xinxing Sun, Naiying Chen, Sicheng Yao, Xun Feng, Yang Chen
Abstract
, intercellular and follicular ones, and the follicular route was shown to be particularly important for ZIF-8@PDA, in which the drug and carrier were co-delivered into the skin as an intact particle. This study provides evidence for using ZIF-8 and PDA modification for skin-specific drug delivery and offers an effective avenue to develop novel nanoplatforms for dermal application to treat skin diseases.
Topics & Concepts
Drug deliveryZeolitic imidazolate frameworkNano-Materials scienceCoatingImidazolateNanotechnologyDrugChemical engineeringComposite materialChemistryMetal-organic frameworkMedicinePharmacologyEngineeringOrganic chemistryAdsorptionSynthesis and properties of polymersAdvancements in Transdermal Drug DeliveryAdvanced Drug Delivery Systems