Toxoplasma gondii-Induced Neutrophil Extracellular Traps Amplify the Innate and Adaptive Response
Farlen José Bebber Miranda, Bruno Coelho Rocha, Milton Pereira, Larissa M. N. Pereira, Erikson H. M. de Souza, Ana Paula M.P. Marino, Pedro Augusto Carvalho Costa, Daniel V. Vasconcelos-Santos, Lis Ribeiro do Valle Antonelli, Ricardo T. Gazzinelli
Abstract
Approximately one-third of the human population is estimated to be chronically infected with the obligate intracellular parasite Toxoplasma gondii . Humans are accidental hosts that are infected with T. gondii after consumption of undercooked meat or contaminated water.
Topics & Concepts
Toxoplasma gondiiNeutrophil extracellular trapsChemokineInnate immune systemImmunologyBiologyInterleukin 8Tumor necrosis factor alphaImmune systemNeutrophil elastaseRespiratory burstCytokineInflammationMicrobiologyAntibodyNeutrophil, Myeloperoxidase and Oxidative MechanismsToxoplasma gondii Research StudiesInflammasome and immune disorders