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Management of acute spinal cord compression in multiple myeloma

Bo Chen, Lin Cai, Fuling Zhou

2020Critical Reviews in Oncology/Hematology27 citationsDOIOpen Access PDF

Abstract

Spinal cord compression (SCC) is a devastating complication of multiple myeloma and has the potential to cause loss of neurological function. The common symptoms of SCC are back pain, motor weakness, and sensory change. Once diagnosed, the patient should be managed as soon as possible to prevent permanent loss of neurological function. Currently, there have been a number of studies describing the mechanism and management experience of SCC in patients with myeloma. The clinical features, diagnostic strategies, and the roles of different therapeutic options are herein reviewed.

Topics & Concepts

MedicineMultiple myelomaComplicationSpinal cord compressionWeaknessSensory lossSpinal cordSurgeryIntensive care medicinePhysical medicine and rehabilitationInternal medicinePsychiatryMultiple Myeloma Research and TreatmentsManagement of metastatic bone diseaseSpine and Intervertebral Disc Pathology
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