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Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

T. Brian, Peggy P. Hsu, Sidney Y. Vermeulen, Zhishan Wang, Taghreed Hirz, Keene L. Abbott, Najihah Aziz, Joseph M. Replogle, Stefan Bjelosevic, Jonathan Paolino, Samantha A. Nelson, Samuel Block, Alicia M. Darnell, Raphaël Ferreira, Hanyu Zhang, Jelena Milosevic, Daniel R. Schmidt, Christopher Chidley, Isaac S. Harris, Jonathan S. Weissman, Yana Pikman, Kimberly Stegmaier, Sihem Cheloufi, Xiaofeng A. Su, David B. Sykes, Matthew G. Vander Heiden

2024Developmental Cell29 citationsDOIOpen Access PDF

Topics & Concepts

BiologyTranscription factorCell biologyDNA replicationGeneticsCell fate determinationDNA re-replicationCell cycleOrigin recognition complexCellDNAProgenitor cellGeneControl of chromosome duplicationEukaryotic DNA replicationStem cellEpigenetics and DNA MethylationDNA Repair MechanismsGenomics and Chromatin Dynamics
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress | Litcius