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Activated NETosis of bone marrow neutrophils up-regulates macrophage osteoclastogenesis via cGAS-STING/AKT2 pathway to promote osteoporosis

Yutong Guo, Hanzhang Zhou, Yixiang Wang, Yan Gu

2025Experimental Cell Research16 citationsDOI

Topics & Concepts

BiologyStingMacrophageBone marrowOsteoporosisImmunologyCell biologyCancer researchEndocrinologyBiochemistryIn vitroEngineeringAerospace engineeringNeutrophil, Myeloperoxidase and Oxidative Mechanismsinterferon and immune responsesImmune cells in cancer
Activated NETosis of bone marrow neutrophils up-regulates macrophage osteoclastogenesis via cGAS-STING/AKT2 pathway to promote osteoporosis | Litcius