Thiocyanation/Cyclization of γ‐hydroxy Olefins to Access Thiocyanato‐Containing Oxygen Heterocyclic Compounds
Chengcheng Li, Pingliang Long, Zhenda Fu, Di Wu, Fu‐Xue Chen, Hongquan Yin
Abstract
Abstract A new thiocyanation/cyclization reaction was developed to synthesize thiocyanato‐containing oxygen heterocyclic compounds with terminal and non‐terminal enols. The approach supplies an efficient method to build the multi‐substituted ring and spiro ring structure of furan, which has a wide range of substrates, good functional group tolerance, and the desired products can be obtained in a medium to high yield.
Topics & Concepts
ChemistryFuranYield (engineering)Ring (chemistry)OxygenReaction conditionsFunctional groupCombinatorial chemistryMolecular oxygenMedicinal chemistryOrganic chemistryStereochemistryCatalysisMetallurgyPolymerMaterials scienceSulfur-Based Synthesis TechniquesSynthesis and Catalytic ReactionsSynthesis of heterocyclic compounds