Dealing with the Foreign‐Body Response to Implanted Biomaterials: Strategies and Applications of New Materials
Donghui Zhang, Qi Chen, Chao Shi, Minzhang Chen, Kaiqian Ma, Jianglin Wan, Runhui Liu
Abstract
Abstract Foreign‐body response caused by implanted biomaterials seriously impedes the function of implants and is a major obstacle to the development of implantable biomaterials and medical devices. Recent advances in implantable biomaterials and medical devices have provided strategies to resist the foreign‐body response. In this review, the mechanism of the foreign‐body response and conventional strategies to mitigate foreign‐body response is briefly introduced. Then, three types of promising foreign‐body response resisting materials are focused and the advantages, characteristics, and applications of each material are discussed. Finally, prospects are put forward for future development of foreign‐body response resisting materials and current challenges that require in‐depth study.