Litcius/Paper detail

Medication Non-adherence in Older Adults: Underlying Factors, Potential Interventions and Outcomes

Elstin Anbu Raj, R Vilakkathala, Johnson George

2025Drugs & Aging9 citationsDOIOpen Access PDF

Abstract

Polypharmacy is very common among older adults and is associated with poor health outcomes. This scoping review aimed to understand the underlying factors for poor medication taking by older patients and potential solutions to mitigate these risks. The ability to take medications and adherence are affected by various factors related to patients, treatments, health conditions and socio-demographics, healthcare providers and the healthcare systems. Educational and behavioural interventions are used alone or in combination for the optimisation medication use. Medication review and deprescribing, including regimen simplification, by trained practitioners has the potential to enhance patient safety and reduce healthcare costs. Engaging the patient and family may bring about additional benefits. Various technology-based interventions to promote self-efficacy are evolving and are used to support consumer self-management.

Topics & Concepts

PolypharmacyMedicinePsychological interventionHealth carePharmacotherapyMedication therapy managementMEDLINEBeers CriteriaDeprescribingPatient safetyOlder peopleRegimenGeriatricsMedication adherenceIntensive care medicineFamily medicineAlternative medicineHealthcare systemSystematic reviewGerontologyQuality of life (healthcare)Medical prescriptionPsychiatryDrugPharmaceutical Practices and Patient OutcomesMedication Adherence and CompliancePharmaceutical studies and practices