Discovery of novel resorcinol biphenyl ether-based macrocyclic small molecules as PD-1/PD-L1 inhibitors with favorable pharmacokinetics for cancer immunotherapy

Zichao Yang, Ziqing Liu, Chenglong Xu, Jian-Wei Xu, Ting Liu, Haiqi He, Ling Li, Yichang Ren, Jianjun Chen