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Medical management of benign prostatic hyperplasia

Eiftu Haile, Ayodeji E. Sotimehin, Bradley C. Gill

2024Cleveland Clinic Journal of Medicine30 citationsDOIOpen Access PDF

Abstract

Medical management of benign prostatic hyperplasia (BPH) has progressed gradually in recent years and remains the starting point for most symptomatic patients seeking treatment. Beyond well-known alpha-blockers and 5-alpha reductase inhibitors, there is growing evidence for the use of phosphodiesterase-5 inhibitors and beta-3 agonists in managing the condition, which may afford additional relief of "bothersome" symptoms in some patients. This review details contemporary medical management of BPH with an emphasis on the indications for certain classes of pharmacotherapy and their relative benefits and side effects. Surgical and procedural treatment of BPH is covered in a separate review.

Topics & Concepts

MedicineHyperplasiaPharmacotherapyMedical therapyUrology5 Alpha-Reductase InhibitorIntensive care medicineGynecologyProstateFinasterideInternal medicineCancerUrinary Bladder and Prostate ResearchHormonal and reproductive studiesSexual function and dysfunction studies
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