The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
Ly Vu, Brian F. Pickering, Yuanming Cheng, Sara Zaccara, Diu Nguyen, Gerard Minuesa, Timothy Chou, Arthur Chow, Yogesh Saletore, Matthew MacKay, Jessica Schulman, Christopher Famulare, Minal Patel, Virginia M. Klimek, Francine E. Garrett-Bakelman, Ari Melnick, Martin Carroll, Christopher E. Mason, Samie R. Jaffrey, Michael G. Kharas
Topics & Concepts
Myeloid leukemiaHaematopoiesisMyeloidProgenitor cellBiologyLeukemiaCancer researchCell biologyCellular differentiationStem cellImmunologyBiochemistryGeneRNA modifications and cancerCancer-related gene regulationRNA Research and Splicing