PDL1-targeted vaccine exhibits potent antitumor activity by simultaneously blocking PD1/PDL1 pathway and activating PDL1-specific immune responses
Hong Tian, Yanliang Kang, Xiaodao Song, Yi Xu, Hongmei Chen, Xingqun Gong, Wanli Zhang, Yun‐Yan Xu, Xuefei Xia, Xiangdong Gao, Wenbing Yao
Topics & Concepts
Immune systemImmunotherapyImmunologyImmune checkpointDownregulation and upregulationBiologyImmunityCancer researchEpitopeBlockadeAntibodyReceptorBiochemistryGeneCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCAR-T cell therapy research