Litcius/Paper detail

LRRC8A contributes to angiotensin II-induced cardiac hypertrophy by interacting with NADPH oxidases via the C-terminal leucine-rich repeat domain

Congde Huo, Yan Liu, Xing Li, Rong Xu, Xin Jia, Liming Hou, Xiaoming Wang

2021Free Radical Biology and Medicine30 citationsDOI

Topics & Concepts

P22phoxNADPH oxidaseNOX4Angiotensin IIChemistryGene knockdownReactive oxygen speciesCytosolNOX1Leucine-rich repeatCell biologyInternal medicineBiologyMolecular biologyBiochemistryEnzymeApoptosisReceptorMedicineIon channel regulation and functionCardiac Fibrosis and RemodelingCardiac electrophysiology and arrhythmias