Stepwise optimization of recombinant protein production in Escherichia coli utilizing computational and experimental approaches
Kulandai Arockia Rajesh Packiam, Ramakrishnan Nagasundara Ramanan, Chien Wei Ooi, Lakshminarasimhan Krishnaswamy, Beng Ti Tey
Topics & Concepts
Escherichia coliRecombinant DNAFermentationProtein expressionSelection (genetic algorithm)Computational biologyBiologyProduction (economics)Biochemical engineeringBiochemistryBiotechnologyChemistryGeneComputer scienceMachine learningEngineeringMacroeconomicsEconomicsViral Infectious Diseases and Gene Expression in InsectsProtein purification and stabilityRNA and protein synthesis mechanisms