Down-Regulating Scar Formation by Microneedles Directly <i>via</i> a Mechanical Communication Pathway
Qing Zhang, Lin Shi, Hong He, Xingmou Liu, Yong Huang, Dan Xu, Mengyun Yao, Ning Zhang, Yicheng Guo, Yifei Lü, Haisheng Li, Junyi Zhou, Jianglin Tan, Malcolm Xing, Gaoxing Luo
Abstract
the mechanotherapeutic strategy is promising for scar-free wound healing.
Topics & Concepts
Extracellular matrixFibronectinFibroblastHypertrophic scarMaterials scienceBiomedical engineeringFibrosisFocal adhesionWound healingBiophysicsCell biologyChemistrySignal transductionAnatomyPathologyMedicineImmunologyBiologyBiochemistryIn vitroCellular Mechanics and InteractionsTendon Structure and TreatmentSilk-based biomaterials and applications